![]() Research from studies of twins and families suggests that there’s a large genetic component to alopecia totalis and universalis, with people more likely to develop this condition if they have a family history of autoimmune hair loss. ![]() While the precise cause of alopecia universalis isn’t known, experts have identified various factors that may contribute to the development of this type of complete hair loss. In very rare cases, alopecia universalis can develop before birth - a condition referred to as alopecia universalis congenita. Hair that grows back white or gray before regaining its natural colorĭevelopment of ridges and pits in the nails Sudden hair loss in round or oval-shaped patchesĬonjoined patches of hair loss that form larger bald spots Less than 10 percent of all people with alopecia areata go on to develop alopecia totalis, with an even smaller percentage developing more advanced alopecia universalis over time.Ĭommon symptoms of alopecia areata include: What Causes Alopecia Universalis?Īt the moment, researchers aren’t aware of precisely why alopecia universalis and other forms of alopecia areata develop.Īlopecia universalis usually begins as alopecia areata. In the entire United States, experts think fewer than 200,000 people are affected by this type of alopecia. Experts think this type of hair loss develops when your immune system identifies, targets and damages your hair follicles, causing your hair to stop growing normally.Ĭompared to male pattern baldness and other types of hair loss, alopecia universalis isn’t very common. Unlike most cases of alopecia areata, which involve small patches of hair loss on the scalp, it can involve complete loss of your scalp hair, facial hair and body hair.Īlopecia universalis is also referred to as “alopecia areata universalis.” When this form of hair loss affects your entire scalp but doesn’t cause significant hair loss on your entire body, it’s commonly referred to as alopecia totalis (AT).Īlopecia universalis and alopecia totalis are both forms of autoimmune hair loss. © 2019 European Academy of Dermatology and Venereology.Alopecia universalis is an uncommon, advanced form of alopecia areata. Response to treatment is often unpredictable, and physicians should be aware of the prognosis and its effects in order to properly counsel patients. The poor long-term outcomes of AT and AU may cause patients to lose hope with treatment. A larger proportion of patients will obtain at least transient recovery periods of partial or total hair regrowth. According to these studies 8.5% (32/375) of AT and AU patients achieved complete recovery. Six of the nine studies identified complete recovery as a potential end point in a total of 375 (39 = AT, 75 = AU, 261 = not specified) patients. The articles described 689 (162 = AT, 245 = AU, 282 = not specified) total patients. A total of nine articles discussing long-term recovery rates of AT and AU were identified. The PubMed database was queried to identify all articles discussing the long-term prognosis of AT and AU. ![]() The goal of this review is to identify all studies with long-term prognostic data on patients with AT and AU and provide a long-term outcome estimate. Alopecia totalis (AT) and universalis (AU) represent the most severe subtypes of alopecia areata with more dramatic features and worse prognosis.
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